Stress Rapidly Increases Biological Age, but Recovery Turns Back the Clock

Stress can cause rapid and transient increases in biological age, which can be reversed upon recovery, according to a new study. Using DNA methylation clocks, researchers found that stress triggers short-term fluctuations in biological age in humans and mice. The findings challenge the idea that biological age has a unidirectional upward trajectory over the life course, and highlights the importance of reducing biological age to improve longevity.