A new study revealed shared cellular and molecular changes in the brains of people with schizophrenia and older adults, pointing to a common biological basis for cognitive impairments in these groups. The study analyzed gene expression in over a million cells from 191 individuals, uncovering a coordinated reduction in genes supporting synaptic connections by neurons and astrocytes, dubbed the Synaptic Neuron and Astrocyte Program (SNAP).
A new study revealed shared cellular and molecular changes in the brains of people with schizophrenia and older adults, pointing to a common biological basis for cognitive impairments in these groups. The study analyzed gene expression in over a million cells from 191 individuals, uncovering a coordinated reduction in genes supporting synaptic connections by neurons and astrocytes, dubbed the Synaptic Neuron and Astrocyte Program (SNAP).
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