A gene named DEK has been identified as potentially responsible for the degeneration of neurons vulnerable to Alzheimer's Disease (AD), particularly in the entorhinal cortex, a critical area for memory formation. By manipulating levels of DEK in experimental models and neurons in vitro, researchers observed increased tau accumulation and neuron degeneration, suggesting a new therapeutic target.
Breakthrough in Understanding Alzheimer's Disease Vulnerability
Neuroscience News - 12 Mar 2024 17:59
A gene named DEK has been identified as potentially responsible for the degeneration of neurons vulnerable to Alzheimer's Disease (AD), particularly in the entorhinal cortex, a critical area for memory formation. By manipulating levels of DEK in experimental models and neurons in vitro, researchers observed increased tau accumulation and neuron degeneration, suggesting a new therapeutic target.
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