A study has found that traumatic brain injury (TBI) increases the risk of Alzheimer's disease by disrupting protein clearance, leading to the accumulation of toxic tau proteins in the brain. Researchers discovered that TBI downregulates BAG3, a protein crucial for clearing damaged proteins, which contributes to Alzheimer's-related tau buildup.
A study has found that traumatic brain injury (TBI) increases the risk of Alzheimer's disease by disrupting protein clearance, leading to the accumulation of toxic tau proteins in the brain. Researchers discovered that TBI downregulates BAG3, a protein crucial for clearing damaged proteins, which contributes to Alzheimer's-related tau buildup.
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