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Pausing Amyloid Fibrils Offers New Alzheimer's Insight

Neuroscience News - 25 Oct 2024 19:55
Pausing Amyloid Fibrils Offers New Alzheimer's Insight Researchers have identified a unique "paused state" in the growth of amyloid β fibrils, linked to Alzheimer's disease, using high-speed atomic force microscopy. In this state, fibril growth is halted, allowing an antibody, 4396C, to bind and prevent further growth, opening a potential path to slow Alzheimer's progression.
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