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Ketone Bodies Clear Damaged Proteins in the Brain

Neuroscience News - 2 Dec 2024 21:10
Ketone Bodies Clear Damaged Proteins in the Brain Ketone bodies, known for their role in energy metabolism during fasting, have been shown to directly interact with damaged proteins in the brain, aiding their clearance through autophagy. Researchers discovered that the ketone body β-hydroxybutyrate alters the solubility of misfolded proteins, facilitating their removal and reducing pathological aggregation.
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