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How Psilocybin Lifts Mood Without the Hallucinogenic Trip

Neuroscience News - 5 Apr 2025 00:19
How Psilocybin Lifts Mood Without the Hallucinogenic Trip Researchers have uncovered two key brain mechanisms--specific neurons and a serotonin receptor--that help explain how psilocybin produces long-lasting antidepressant effects. Their study identified pyramidal tract neurons in the medial frontal cortex and the serotonin 5-HT2A receptor as essential to the therapeutic action of psilocybin.
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