Researchers demonstrated that systemic factors from young mice can rejuvenate the aging retina by alleviating cellular senescence and restoring function. Using heterochronic parabiosis and single-cell RNA sequencing, the study identified AdipoR1 and its downstream AMPK signaling as key drivers of retinal rejuvenation.
Researchers demonstrated that systemic factors from young mice can rejuvenate the aging retina by alleviating cellular senescence and restoring function. Using heterochronic parabiosis and single-cell RNA sequencing, the study identified AdipoR1 and its downstream AMPK signaling as key drivers of retinal rejuvenation.
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