Scientists have uncovered how stem cells in the olfactory system continually regenerate neurons responsible for our sense of smell. Using live zebrafish imaging, cell tracking, and single-cell RNA sequencing, researchers identified a bistable toggle switch that drives progenitor cells to commit to specific fates and self-organize into cellular neighborhoods.
Scientists have uncovered how stem cells in the olfactory system continually regenerate neurons responsible for our sense of smell. Using live zebrafish imaging, cell tracking, and single-cell RNA sequencing, researchers identified a bistable toggle switch that drives progenitor cells to commit to specific fates and self-organize into cellular neighborhoods.
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