Scientists have discovered that rogue DNA rings, called extrachromosomal DNA (ecDNA), appear early in glioblastoma and drive its rapid growth and resistance to therapy. By combining patient data, imaging, and computational modeling, researchers found that ecDNA often carries the EGFR cancer gene and its aggressive variants.
Scientists have discovered that rogue DNA rings, called extrachromosomal DNA (ecDNA), appear early in glioblastoma and drive its rapid growth and resistance to therapy. By combining patient data, imaging, and computational modeling, researchers found that ecDNA often carries the EGFR cancer gene and its aggressive variants.
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