Researchers have shown for the first time that flipping an epigenetic switch in specific memory-holding neurons can directly alter memory strength. By targeting the gene Arc-which helps neurons adjust their connections-scientists used CRISPR-based tools to either boost or silence its activity in engram cells within the hippocampus.
Researchers have shown for the first time that flipping an epigenetic switch in specific memory-holding neurons can directly alter memory strength. By targeting the gene Arc-which helps neurons adjust their connections-scientists used CRISPR-based tools to either boost or silence its activity in engram cells within the hippocampus.
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