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How Chemotherapy Triggers Nerve Damage, and How to Stop It

Neuroscience News - 29 Oct 2025 20:51
How Chemotherapy Triggers Nerve Damage, and How to Stop It A new study reveals that chemotherapy-induced nerve pain arises from a stress response in immune cells that triggers inflammation and neurotoxicity. Researchers found that activating a cellular stress sensor called IRE1 causes nerve damage and pain during chemotherapy, but blocking it prevents both in mice.
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