New research reveals that neurons release a little-understood extracellular kinase called VLK to strengthen synaptic connections, providing a missing piece in how the nervous system adapts during learning and pain. The kinase phosphorylates EphB receptors outside the cell, which recruits NMDA receptors and amplifies synaptic signaling.
New research reveals that neurons release a little-understood extracellular kinase called VLK to strengthen synaptic connections, providing a missing piece in how the nervous system adapts during learning and pain. The kinase phosphorylates EphB receptors outside the cell, which recruits NMDA receptors and amplifies synaptic signaling.
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